The ADDM and CADDRE Programs

The Centers for Disease Control and Prevention (CDC), National Center on Birth Defects and Developmental Disabilities have awarded a series of multi-year cooperative agreements to states or their designated entities to establish autism surveillance programs, the Autism and Developmental Disabilities Monitoring Network (ADDM), and the Centers of Excellence for Autism and Developmental Disabilities Research and Epidemiology (CADDRE). Currently there are six funded CADDRE sites and sixteen funded ADDM projects.

MSU Data Coordinating Center’s role on the CDC ADDM & CADDRE Programs

Currently the National Center on Birth Defects and Developmental Disabilities of CDC (Centers for Disease Control and Prevention) has funded the MSU-DCC to serve as the data coordinating center for two national studies of child autism spectrum disorders:

ADDM-CADDRE Surveillance Study

The Autism and Developmental Disabilities Network (ADDM) aims to measure the number of cases of autism and other developmental disabilities in different regions of this country to provide accurate, population-based estimates of the prevalence of these disabilities in young children. The ADDM-CADDRE study network aims to identify the occurrences of ASDs in ~500,000 births within catchment areas in 18 states.

Links to ADDM Sites

• Alabama
  • University of Alabama, Birmingham, AL
• Arizona
  • University of Arizona, Tuscon, AZ
• Arkansas
  • University of Arkansas for Medical Sciences, North Little Rock, AR
• Florida
  • University of Miami, Coral Gables, FL (CDC)
  • University of Miami Center for Autism and Related Disabilities, Coral Gables, FL
• Georgia
  • National Center on Birth Defects and Developmental Disabilities (CDC), Atlanta, GA
• Missouri/Illinois
  • Washington University, St. Louis, MO
• New Jersey
  • New Jersey Medical School, Newark, NJ
• South Carolina
  • Medical University of South Carolina, Charleston, SC
• Utah
  • Utah Department of Health & Utah School of Medicine, Salt Lake City, Utah
• West Virginia
  • Marshall University, Huntington, WV (CDC)
  • Marshall University, Huntington, WV pdf
• Wisconsin
  • University of Wisconsin-Madison, Madison, WI
  • University of Wisconsin-Madison, Madison, WI pdf
• Maryland/Delaware
  • Johns Hopkins University, Baltimore, MD -ADDM

CADDRE National Study

The CDC established six Centers of Excellence for Autism and Developmental Disabilities Research and Epidemiology (CADDRE) per the Children’s Health Act of 2000. The six centers are executing a population-based multi-site study (case-cohort design) to investigate potential risk factors for Autism Spectrum Disorders. The study sample size of 3-5 year olds in 24-month birth cohort will be larger than other epidemiologic ASD investigations of the causes of autism (~6000 individuals), and will involve detailed case assessment of other accompanying symptoms and diseases. The study will collect and archive buccal (cheek) swabs, blood, and hair biosamples.

Links to CADDRE Sites

• California
  • California Department of Health Services, Oakland, CA
  • California Department of Health Services, Oakland, CA (CDC)
• Colorado
  • Colorado Department of Public Health and Environment, Denver, CO
• Maryland/Delaware
  • Johns Hopkins University, Baltimore, MD
  • Johns Hopkins University, Baltimore, MD (CDC)
• Georgia
  • National Center on Birth Defects and Developmental Disabilities (CDC), Atlanta, GA
• North Carolina
  • University of North Carolina, Chapel Hill, NC
  • University of North Carolina, Chapel Hill, NC (CDC)
• Pennsylvania
  • University of Pennsylvania/The Children’s Hospital of Philadelphia, Philadelphia, PA

US Map Showing Distribution of CADDRE & ADDM States

[printable version]